This page is not the official website. Generated by AI, does not constitute any advice. If needed, please click here to visit the corresponding official website.

Antengene Logo Visit Website

Treating Patients Beyond Borders

Antengene is a global, R&D-driven, commercial-stage biotech company focused on developing first-in-class and best-in-class therapies for hematologic malignancies and solid tumors with significant unmet medical needs.

A Leader in the Search for Breakthrough Therapies

Antengene Corporation Limited (SEHK: 6996.HK) is a global, R&D-driven, commercial-stage biotech company focused on developing first-in-class and best-in-class therapeutics for diseases with significant unmet medical needs. Our pipeline spans from preclinical to commercial stages and includes several in-house discovered programs.

  • 31 investigational new drug (IND) approvals in the U.S. and Asia
  • New drug applications (NDAs) submitted in 11 Asia Pacific markets
  • Lead commercial asset XPOVIO® approved across 10 markets
  • Included in national reimbursement schemes in 5 markets
Read Full Company Profile →
Antengene Research Lab

Our Vision

Developing innovative cancer medicines to treat patients beyond borders worldwide.

Our Mission

Building fully-integrated capabilities in discovery, clinical development, manufacturing, and commercialization to foster the rapid clinical adoption of innovative medicines for the benefit of broad patient populations.

Innovative R&D Pipeline

Our proprietary platforms and in-house discovery programs are driving the next generation of targeted cancer therapies.

AnTenGager™ TCE 2.0 Platform

A proprietary T cell engager 2.0 platform featuring:

  • • “2+1” bivalent binding for low-expressing targets
  • • Steric hindrance masking to reduce off-target effects
  • • Proprietary CD3 sequences with fast on/off kinetics
  • • Minimizes cytokine release syndrome (CRS) and enhances efficacy

Supports broad applicability across autoimmune diseases, solid tumors, and hematological malignancies.

First/Best-in-Class Therapies

ATG-022 (CLDN18.2 ADC)

Phase II program efficacious in Claudin 18.2 ultra-low expressors

ATG-037 (CD73 Inhibitor)

Oral small molecule with robust PoC data in reversing anti-PD-1 resistance

ATG-101 (PD-L1 × 4-1BB)

Bispecific antibody overcoming liver toxicity

ATG-031 (CD24-targeting)

First-in-class macrophage activator targeting CD24-expressing solid tumors

Our Products & Pipeline

From discovery to commercialization, our pipeline is designed to deliver transformative therapies to patients worldwide.

XPOVIO® (selinexor)

XPOVIO® / Selinexor

Approved in 10 markets including Mainland China, Hong Kong, South Korea, Singapore, and Australia. Used in multiple myeloma and DLBCL.

Commercialized Hematologic Malignancy
ATG-022 (CLDN18.2 ADC)

ATG-022

Claudin 18.2-targeting antibody-drug conjugate (ADC) for gastric/GEJ cancers, including ultra-low expressors.

Phase II Solid Tumor
ATG-037 (CD73 Inhibitor)

ATG-037

Oral CD73 inhibitor with potential to reverse resistance to anti-PD-1 therapies in melanoma and NSCLC.

Phase II Immuno-Oncology
ATG-101 (PD-L1 × 4-1BB)

ATG-101

Bispecific antibody targeting PD-L1 and 4-1BB, designed to overcome liver toxicity seen in other 4-1BB agonists.

Phase I Solid Tumor
ATG-031 (CD24-targeting)

ATG-031

First-in-class macrophage activator targeting CD24-expressing solid tumors, harnessing innate immunity.

Phase I Solid Tumor
Preclinical

ATG-042

Oral PRMT5-MTA inhibitor with potential in hematologic and solid tumors.

Preclinical Oncology
Discovery

AnTenGager™ Programs

Multiple T cell engager candidates in development for autoimmune and oncology indications.

Discovery Autoimmune / Oncology
Clinical

Ongoing Clinical Trials

Multiple trials across Asia and the U.S. in gastric cancer, lymphoma, melanoma, and NSCLC.

Global Trials Multi-Indication
View Full Pipeline

Latest News & Updates

Stay informed about Antengene’s latest clinical milestones, regulatory approvals, and partnerships.

December 03, 2025

XPOVIO® Approved in Hong Kong for Two Additional Indications

Expanding access in multiple myeloma and diffuse large B-cell lymphoma.

Read More →
December 02, 2025

IND Approval in China for ATG-022 + KEYTRUDA® Study

Phase Ib/II trial evaluating combination in gastric cancer patients.

Read More →
November 20, 2025

Antengene Hosts 2025 R&D Day

Showcasing encouraging clinical data and progress across investigational programs.

Read More →
View All News →

Global Collaborations

Antengene is working closely with global partners to usher in the next wave of biopharmaceutical innovation.

If you are interested in partnering with Antengene, please contact us at [email protected].

Email Partnership Team

Get in Touch

For business development, media inquiries, or career opportunities, visit the official Antengene website to connect with the team.

Notice for Buyers: If you are a buyer, the above information is generated by AI collection and does not constitute any advice. If necessary, please visit the corresponding official website.

For Domain Owners: If you are the domain owner and do not want to be included by fobcompany.info, please contact [email protected] via your corporate email to cancel. We will cancel your inclusion within 3 business days.

如果您是域名所有者 不想被fobcompany.info收录 请用企业邮箱联系[email protected] 取消收录 我们将在3个工作日取消您的收录

Service Request: If you are other domain and want to be included, please contact [email protected]

如果您是其他域名合作 也请联系[email protected]