Advanced Filtration Solutions for Biopharmaceuticals

Hangzhou Guidling Technology Co., Ltd is a trusted manufacturer of ultrafiltration cassettes, TFF systems, hollow fiber filters, and virus removal technologies — delivering precision, scalability, and reliability across lab, pilot, and production scales.

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Industrial Fluid Filtration

From culture media to fermentation clarification, our solutions ensure purity and efficiency.

Lab to Production Scale

Seamless transition from sample processing to large-scale biopharmaceutical production.

Certified Quality

Established in 2015 with official certifications in biopharma filtration and purification.

About GUIDLING

Hangzhou Guidling Technology Co., Ltd is an innovative manufacturer focused on providing downstream solutions in the biopharmaceutical industry — including clarification, separation, concentration, and purification.

Since our founding in 2015, we have developed five core product series: ultrafiltration & microfiltration cassettes, tangential flow filtration (TFF) systems, stainless steel holders, centrifugal filter devices, depth filters, and virus clearance filters. These products meet the rigorous demands of concentration, desalination, virus removal, and fermentation clarification in biological products.

Our solutions are widely used in the production of antibodies, vaccines, diagnostics, blood products, polysaccharides, endotoxin filtration, viruses, and culture media — serving both biopharmaceutical and industrial fluid filtration markets.

Company Profile

Our Strengths

Professional After Sales Service

We recommend suitable products before purchase and provide ongoing support during usage.

Official Certification

Established in 2015 with expertise in biopharma, cell culture, purification, and separation.

No.1 Sales Volume

5 product series and 6 types developed for downstream purification in biopharmaceuticals.

Sustainable Development

Located in Hangzhou with 5 production lines, producing 8,000 cassettes and 5,000 holders monthly.

Our Products

From laboratory sample processing to full-scale production, GUIDLING offers a comprehensive range of filtration solutions tailored to your biopharmaceutical needs.

Ultrafiltration Cassettes

Ideal for concentration and desalination processes in antibody and vaccine production.

Available in multiple molecular weight cut-offs
High flux and low protein binding
Compatible with standard TFF systems

Tangential Flow Filtration System

Complete systems for scalable purification and concentration in bioprocessing.

Automated and manual options
Scalable from lab to production
Integrated pumps and sensors

Stainless Steel Holder (0.1–2.5㎡)

Durable holders for membrane cassettes, supporting various filtration areas.

Corrosion-resistant 316L stainless steel
Leak-proof sealing design
Easy to clean and sterilize

Centrifugal Ultrafiltration Device

Compact devices for rapid sample concentration and buffer exchange.

Multiple MWCO options
Low retention volume
Suitable for small-volume samples

Depth Filtration Capsule

Efficient pre-filtration for cell debris and particulates in fermentation broth.

High dirt-holding capacity
Low pressure drop
Single-use and reusable options

Virus Removal Filters

Critical safety step for biologics with 20nm pore size for effective virus clearance.

20nm virus filter available
Syringe and capsule formats
Validated for clearance efficiency

Hollow Fiber Membrane

High-efficiency membranes for concentration, dialysis, and cell separation.

PES and other polymer options
High surface area-to-volume ratio
Used in TFF and perfusion systems

Microfiltration Cassettes

Designed for cell separation, clarification, and particle removal in bioprocessing.

Pore sizes from 0.1 to 1.0 µm
Low fouling membrane materials
Compatible with standard holders

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Why Choose GUIDLING?

Scalability

Seamless transition from lab-scale R&D to full production with compatible systems and cassettes.

High Purity & Safety

Our virus filters and sterile filtration solutions ensure product safety and regulatory compliance.

High Efficiency

Optimized membrane design delivers high flux, low fouling, and excellent recovery rates.

Complete Systems

From cassettes to holders and TFF systems, we offer integrated solutions for your workflow.

Global Support

Multilingual support and international shipping to serve clients worldwide.

Sustainable Manufacturing

Eco-conscious production with efficient resource use and quality control.

Frequently Asked Questions

What applications are your ultrafiltration cassettes used for?

Our ultrafiltration cassettes are used for concentration, desalination, buffer exchange, and purification in antibody, vaccine, and protein production.

Do you offer custom filtration solutions?

Yes, we provide tailored filtration systems and membrane configurations based on client requirements for flow rate, area, and MWCO.

Are your products compatible with existing TFF systems?

Yes, our cassettes and holders are designed to be compatible with most standard TFF equipment from major brands.

What is the difference between depth filters and membrane filters?

Depth filters remove particulates through a thick matrix, ideal for pre-filtration. Membrane filters use a thin, precise pore structure for sterilization or fractionation.

How do I choose the right MWCO for my application?

Select a MWCO that is 3–5 times smaller than the target molecule to retain it, while allowing smaller contaminants to pass through.

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